University Of Michigan Cancer Genetics Program

The Genetics Graduate Program was developed in 1970 as an interdepartmental degree-granting program that provides graduate education in the field of genetics, and over 200 alumni have received PhD degrees in Genetics. Download metin2 ro item shop hack v2.0. The program is administered through the College of Natural Science, and participating faculty have academic appointments in various MSU departments or institutions affiliated with MSU.

• University Of Michigan Genetics Department
• University Of Michigan
• Genetic Counseling University Of Michigan
• University Of Michigan Genetic Testing
• University Of Michigan Cancer Clinical Trials

The Department of Human Genetics is dedicated to basic scientific research in human genetics and genetic disease, as well as the training of the next generation of scientists and health care providers.

Our faculty explore three broad areas of human genetics: molecular genetics, genetic disease, and statistical/population genetics. Within molecular genetics, research groups study DNA repair and recombination, genome instability, gene function and regulation, epigenetics, RNA modification and control, and genomic systems. Research in human genetic disease emphasizes the genetics of development, neurogenetics, stem cell biology, medical genetics, reproductive sciences, and the genetics of cancer. Evolutionary and population genetics research includes statistical tools for genetics, genetic epidemiology, and genetic mapping of complex traits and diseases.

University Of Michigan Genetics Department

We invite you to explore our faculty, students, graduate programs, courses, and events/seminars.

Featured Publications

Wilson TE, Sunder S. Double-strand breaks in motion: implications for chromosomal rearrangement. Curr Genet. 2019 Jul 18. doi: 10.1007/s00294-019-01015-4. [Epub ahead of print] Review. PubMed PMID: 31321486.

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Jacher JE, Roy N, Ghaziuddin M, Innis JW. Expanding the phenotypic spectrum of MBOAT7-related intellectual disability. Am J Med Genet B Neuropsychiatr Genet. 2019 Jul 8. doi: 10.1002/ajmg.b.32749. [Epub ahead of print] PubMed PMID: 31282596.

https://pettoheves.tistory.com/4. Lenk GM, Park YN, Lemons R, Flynn E, Plank M, Frei CM, Davis MJ, Gregorka B, Swanson JA, Meisler MH, Kitzman JO. CRISPR knockout screen implicates three genes in lysosome function. Sci Rep. 2019 Jul 3;9(1):9609. Jumpstart dumper ? ?. doi: 10.1038/s41598-019-45939-w. PubMed PMID: 31270356; PubMed Central PMCID: PMC6610096.

Sunder S, Wilson TE. Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast. Proc Natl Acad Sci U S A. 2019 Apr 24. pii: 201818595. doi: 10.1073/pnas.1818595116. [Epub ahead of print] PubMed PMID: 31019070.

Ramdas S, Ozel AB, Treutelaar MK, Holl K, Mandel M, Woods LCS, Li JZ. Extended regions of suspected mis-assembly in the rat reference genome. Sci Data. 2019 Apr 23;6(1):39. doi: 10.1038/s41597-019-0041-6. PubMed PMID: 31015470; PubMed Central PMCID: PMC6478900.

Graham SE, Nielsen JB, Zawistowski M, Zhou W, Fritsche LG, Gabrielsen ME, Skogholt AH, Surakka I, Hornsby WE, Fermin D, Larach DB, Kheterpal S, Brummett CM, Lee S, Kang HM, Abecasis GR, Romundstad S, Hallan S, Sampson MG, Hveem K, Willer CJ. Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis. Nat Commun. 2019 Apr 23;10(1):1847. doi: 10.1038/s41467-019-09861-z. PubMed PMID: 31015462; PubMed Central PMCID: PMC6478837.

Flasch DA, Macia Á, Sánchez L, Ljungman M, Heras SR, García-Pérez JL, Wilson TE, Moran JV. Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication. Cell. 2019 May 2;177(4):837-851.e28. doi: 10.1016/j.cell.2019.02.050. Epub 2019 Apr 4. PubMed PMID: 30955886.

University Of Michigan

Harris C, Cloutier M, Trotter M, Hinten M, Gayen S, Du Z, Xie W, Kalantry S. Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2. Elife. 2019 Apr 2;8. pii: e44258. doi: 10.7554/eLife.44258. [Epub ahead of print] PubMed PMID: 30938678.

Genetic Counseling University Of Michigan

Caglayan AO, Gumus H, Sandford E, Kubisiak TL, Ma Q, Ozel AB, Per H, Li JZ, Shakkottai VG, Burmeister M. COQ4 Mutation Leads to Childhood-Onset Ataxia Improved by CoQ10 Administration. Cerebellum. 2019 Mar 8. doi: 10.1007/s12311-019-01011-x. [Epub ahead of print] PubMed PMID: 30847826.

University Of Michigan Genetic Testing

Kuo ME, Theil AF, Kievit A, Malicdan MC, Introne WJ, Christian T, Verheijen FW, Smith DEC, Mendes MI, Hussaarts-Odijk L, van der Meijden E, van Slegtenhorst M, Wilke M, Vermeulen W, Raams A, Groden C, Shimada S, Meyer-Schuman R, Hou YM, Gahl WA, Antonellis A, Salomons GS, Mancini GMS. Cysteinyl-tRNA Synthetase Mutations Cause a Multi-System, Recessive Disease That Includes Microcephaly, Developmental Delay, and Brittle Hair and Nails. Am J Hum Genet. 2019 Mar 7;104(3):520-529. doi: 10.1016/j.ajhg.2019.01.006. Epub 2019 Feb 26. PubMed PMID: 30824121; PubMed Central PMCID: PMC6407526.

University Of Michigan Cancer Clinical Trials

Halo JV, Pendleton AL, Jarosz AS, Gifford RJ, Day ML, Kidd JM. Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids. Retrovirology. 2019 Mar 7;16(1):6. doi: 10.1186/s12977-019-0468-z. PMID: 30845962.